Publications

An archaeal genetic code with all TAG codons as pyrrolysine article

Kivenson, V.; Peters, S. L.; Borrel, G.; Kivenson, A.; Roe, L. T.; Hamlish, N. X.; Fadhlaoui, K.; Schepartz, A.; Gribaldo, S.; Hettich, R. L.; Banfield, J. F.
Science (2025)

Backbone extension acyl rearrangements edit cellular proteins to install β-, γ- and δ-backbones research briefing

Roe, L. T. & Schepartz, A.
Nature Chemical Biology (2025)

AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid article

Chen, D. F.*; Roe, L. T.*; Li, Y.; Borges, A. L.; Zhang, J. Y.; Babbar, P.; Maji, S.; Stevens, M. G. V.; Correy, G. J.; Diolaiti, M. E.; Smith, D. H.; Ashworth, A.; Stroud, R. M.; Kelly, M. J. S.; Bondy-Denomy, J.; Fraser, J. S.
mBio (2025)

Site-selective protein editing by backbone extension acyl rearrangements article

Roe, L. T.; Piper, I. M.; Schissel, C. K.; Dover, T. L.; Shah, B.; Hamlish, N. X.; Garapaty, A. M.; Zheng, S.; Dilworth, D. A.; Wong, N.; Zhang, Z.; Chatterjee, A.; Francis, M. B.; Miller, S. J.; Schepartz, A.
Nature Chemical Biology (2025)

Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo article

Fricke, R.*; Swenson, C. V.*; Roe, L. T.; Hamlish, N. X.; Shah, B.; Zhang, Z.; Ficaretta, E.; Ad, O.; Smaga, S.; Gee, C. L.; Chatterjee, A.; Schepartz, A.
Nature Chemistry (2023)

Cooperative Intramolecular Hydrogen Bonding Strongly Enforces cis-Peptoid Folding article

Wijaya, A. W.*; Nguyen, A. I.*; Roe, L. T.; Butterfoss, G. L.; Spencer, R. K.; Li, N. K.; Zuckermann, R. N.
Journal of the American Chemical Society (2019)

Unconstrained peptoid tetramer exhibits a predominant conformation in aqueous solution article

Roe, L. T.; Pelton, J. G.; Edison, J. R.; Butterfoss, G. L.; Tresca, B. W.; LaFaye, B. A.; Whitelam, S.; Wemmer, D. E.; Zuckermann, R. N.
Biopolymers (2019)